Trilostane has recently received FDA approval as a drug treatment for dogs with Cushing’s syndrome.
Some veterinarians have already been using Trilostane, obtaining it through a complicated importation process, because of Trilostane’s ability to halt the Cushing’s syndrome without doing further damage to the dog’s body.
Read more at Associated Content from Yahoo: Trilostane, New Drug Treatment for Dogs with Cushing’s Syndrome
Update: Is lower-dose trilostane the answer?
Trilostane inhibits the enzyme system involved in the synthesis of cortisol and aldosterone.
Currently the manufacturer recommends a dose of 2.2 to 6.7 mg/kg given orally once a day. Recent studies, however, have shown that dogs can be successfully managed on lower doses and may in fact have fewer adverse events if treated with a twice-daily instead of once-daily approach.
Read more at dvm360: Hyperadrenocorticism: Is lower-dose trilostane the answer?
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Filed under: Cushing's